Publications

2023

Δ9‐Tetrahydrocannabinol self‐administration induces cell type‐specific adaptations in the nucleus accumbens core
Constanza Garcia-Keller, Madeline Hohmeister, Kailyn Seidling, Lauren Beloate, Vivian Chioma, Sade Spencer, Peter Kalivas, Daniela Neuhofer
Addiction Biology  ·  06 Jul 2023  ·  doi:10.1111/adb.13286

2022

Assessing combined effects of varenicline and N‐acetylcysteine on reducing nicotine seeking in rats
Rusty W. Nall, Lauren N. Beloate, Michael E. Meyerink, Tiffany Penaloza, Jade Doolittle, Brett Froeliger, Peter W. Kalivas, Constanza Garcia‐Keller
Addiction Biology  ·  22 Feb 2022  ·  doi:10.1111/adb.13151
Cannabinoid use is enhanced by stress and changes conditioned stress responses
Ritchy Hodebourg, Michael E. Meyerink, Ayteria D. Crow, Carmela M. Reichel, Peter W. Kalivas, Constanza Garcia-Keller
Neuropsychopharmacology  ·  10 Feb 2022  ·  doi:10.1038/s41386-022-01287-4

2021

Adolescent exposure to delta-9-tetrahydrocannabinol and ethanol heightens sensitivity to fear stimuli
Cora E. Smiley, Heyam K. Saleh, Katherine E. Nimchuk, Constanza Garcia-Keller, Justin T. Gass
Behavioural Brain Research  ·  01 Oct 2021  ·  doi:10.1016/j.bbr.2021.113517
∆9-Tetrahydrocannabinol Self-Administration Induces Cell-Type Specific Adaptations and cFOS Expression in the Nucleus Accumbens Core
Daniela Neuhofer, Constanza Garcia-Keller, Madeline Hohmeister, Kailyn Seidling, Lauren Beloate, Vivian Chioma, Sade Spencer, Peter Kalivas
Research Square Platform LLC  ·  27 Sep 2021  ·  doi:10.21203/rs.3.rs-864738/v1
Behavioral and accumbens synaptic plasticity induced by cues associated with restraint stress
Constanza Garcia-Keller, Jordan S. Carter, Anna Kruyer, Angela M. Kearns, Jordan L. Hopkins, Ritchy Hodebourg, Peter W. Kalivas, Carmela M. Reichel
Neuropsychopharmacology  ·  05 Jul 2021  ·  doi:10.1038/s41386-021-01074-7

2020

Relapse-Associated Transient Synaptic Potentiation Requires Integrin-Mediated Activation of Focal Adhesion Kinase and Cofilin in D1-Expressing Neurons
Constanza Garcia-Keller, Michael D. Scofield, Daniela Neuhofer, Swathi Varanasi, Matthew T. Reeves, …, James Pickel, Bruce T. Hope, Brandon K. Harvey, Christopher W. Cowan, Peter W. Kalivas
The Journal of Neuroscience  ·  13 Oct 2020  ·  doi:10.1523/JNEUROSCI.2666-19.2020

2019

Accumbens neuroimmune signaling and dysregulation of astrocytic glutamate transport underlie conditioned nicotine‐seeking behavior
Mark D. Namba, Yonatan M. Kupchik, Sade M. Spencer, Constanza Garcia‐Keller, Julianna G. Goenaga, Gregory L. Powell, Ian A. Vicino, Ian B. Hogue, Cassandra D. Gipson
Addiction Biology  ·  22 Jul 2019  ·  doi:10.1111/adb.12797
N‐Acetylcysteine treatment during acute stress prevents stress‐induced augmentation of addictive drug use and relapse
Constanza Garcia‐Keller, Cora Smiley, Cara Monforton, Samantha Melton, Peter W. Kalivas, Justin Gass
Addiction Biology  ·  07 Jul 2019  ·  doi:10.1111/adb.12798
Ventral Pallidum Is the Primary Target for Accumbens D1 Projections Driving Cocaine Seeking
Thibaut R. Pardo-Garcia, Constanza Garcia-Keller, Tiffany Penaloza, Christopher T. Richie, James Pickel, Bruce T. Hope, Brandon K. Harvey, Peter W. Kalivas, Jasper A. Heinsbroek
The Journal of Neuroscience  ·  08 Jan 2019  ·  doi:10.1523/JNEUROSCI.2822-18.2018

2018

A Model of Δ9-Tetrahydrocannabinol Self-administration and Reinstatement That Alters Synaptic Plasticity in Nucleus Accumbens
Sade Spencer, Daniela Neuhofer, Vivian C. Chioma, Constanza Garcia-Keller, Danielle J. Schwartz, Nicholas Allen, Michael D. Scofield, Tara Ortiz-Ithier, Peter W. Kalivas
Biological Psychiatry  ·  01 Oct 2018  ·  doi:10.1016/j.biopsych.2018.04.016